Cooperating H3N2 Influenza Virus Variants Are Not Detectable in Primary Clinical Samples

ABSTRACT The high mutation rates of RNA viruses lead to rapid genetic diversification, which can enable cooperative interactions between variants in a viral population. We previously described two distinct variants of H3N2 influenza virus that cooperate in cell culture. These variants differ by a si...

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Bibliographic Details
Main Authors: Katherine S. Xue, Alexander L. Greninger, Ailyn Pérez-Osorio, Jesse D. Bloom
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00552-17