Diosmin and Trolox Have Anti-Arthritic, Anti-Inflammatory and Antioxidant Potencies in Complete Freund’s Adjuvant-Induced Arthritic Male Wistar Rats: Roles of NF-κB, iNOS, Nrf2 and MMPs

Diosmin and Trolox Have Anti-Arthritic, Anti-Inflammatory and Antioxidant Potencies in Complete Freund’s Adjuvant-Induced Arthritic Male Wistar Rats: Roles of NF-κB, iNOS, Nrf2 and MMPs

Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease caused by a malfunction of the immune system. The aim of this study was to examine the anti-arthritic effects and suggest the mechanisms of actions of diosmin and trolox in male Wistar rats. Complete Freund’s adjuvant (CFA) was...

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Bibliographic Details
Main Authors: Huda H. Shaaban, Walaa G. Hozayen, Amal K. Khaliefa, Ayman E. El-Kenawy, Tarek M. Ali, Osama M. Ahmed
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
diosmin
trolox
inflammation
rheumatoid arthritis
rats
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/11/9/1721

Internet

https://www.mdpi.com/2076-3921/11/9/1721

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