High Stromal SFRP2 Expression in Urothelial Carcinoma Confers an Unfavorable Prognosis

BackgroundUrothelial carcinoma (UC) patients often bear clinical and genetic heterogeneity, which may differ in management and prognosis. Especially, patients with advanced/metastatic UC generally have a poor prognosis and survive for only few months. The Wnt/β-catenin signaling is found to be highl...

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Main Authors: Hong-Yue Lai, Chia-Chun Chiu, Yu-Hsuan Kuo, Hsin-Hwa Tsai, Li-Ching Wu, Wen-Hsin Tseng, Chien-Liang Liu, Chung-Hsi Hsing, Steven K. Huang, Chien-Feng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.834249/full