The <i>CFTR</i> Gene Germline Heterozygous Pathogenic Variants in Russian Patients with Malignant Neoplasms and Healthy Carriers: 11,800 WGS Results

The <i>CFTR</i> Gene Germline Heterozygous Pathogenic Variants in Russian Patients with Malignant Neoplasms and Healthy Carriers: 11,800 WGS Results

More than 275 million people in the world are carriers of a heterozygous mutation of the <i>CFTR</i> gene, associated with cystic fibrosis, the most common autosomal recessive disease among Caucasians. Some recent studies assessed the association between carriers of <i>CFTR</i&g...

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Bibliographic Details
Main Authors: Maria Makarova, Marina Nemtsova, Anastasiia Danishevich, Denis Chernevskiy, Maxim Belenikin, Anastasiia Krinitsina, Elena Baranova, Olesya Sagaydak, Maria Vorontsova, Igor Khatkov, Lyudmila Zhukova, Natalia Bodunova, Sergey Nikolaev, Mariya Byakhova, Anna Semenova, Vsevolod Galkin, Saida Gadzhieva
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
cystic fibrosis
<i>CFTR</i>
hereditary cancer predisposition syndrome
the frequency of heterozygous carriage
Russian cohort of patients
Online Access:https://www.mdpi.com/1422-0067/24/9/7940

Internet

https://www.mdpi.com/1422-0067/24/9/7940

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