Identifying nucleic acid-associated proteins in Mycobacterium smegmatis by mass spectrometry-based proteomics

Identifying nucleic acid-associated proteins in Mycobacterium smegmatis by mass spectrometry-based proteomics

Abstract Background Transcriptional responses required to maintain cellular homeostasis or to adapt to environmental stress, is in part mediated by several nucleic-acid associated proteins. In this study, we sought to establish an affinity purification-mass spectrometry (AP-MS) approach that would e...

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Bibliographic Details
Main Authors: Nastassja L. Kriel, Tiaan Heunis, Samantha L. Sampson, Nico C. Gey van Pittius, Monique J. Williams, Robin M. Warren
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Molecular and Cell Biology
Subjects:
RNA polymerase
Mycobacterium
Affinity-purification
Nucleic acid-associated proteins
Online Access:http://link.springer.com/article/10.1186/s12860-020-00261-6

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http://link.springer.com/article/10.1186/s12860-020-00261-6

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