Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis

Kallikrein-related peptidases (KLKs) and matrix metalloproteinases (MMPs) are secretory proteinases known to proteolytically process components of the extracellular matrix, modulating the pericellular environment in physiology and in pathologies. The interconnection between these families remains el...

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Bibliographic Details
Main Authors: Katherine Falkowski, Ewa Bielecka, Ida B. Thøgersen, Oliwia Bocheńska, Karolina Płaza, Magdalena Kalińska, Laura Sąsiadek, Małgorzata Magoch, Aleksandra Pęcak, Magdalena Wiśniewska, Natalia Gruba, Magdalena Wysocka, Anna Wojtysiak, Magdalena Brzezińska-Bodal, Kamila Sychowska, Anastasija Pejkovska, Maren Rehders, Georgina Butler, Christopher M Overall, Klaudia Brix, Grzegorz Dubin, Adam Lesner, Andrzej Kozik, Jan J. Enghild, Jan Potempa, Tomasz Kantyka
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
kallikrein 14
membrane-type MMP
CleavEx
fusion protein
zymogen activation
Online Access:https://www.mdpi.com/1422-0067/21/12/4383

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https://www.mdpi.com/1422-0067/21/12/4383

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