Exploring the K+ binding site and its coupling to transport in the neurotransmitter:sodium symporter LeuT
The neurotransmitter:sodium symporters (NSSs) are secondary active transporters that couple the reuptake of substrate to the symport of one or two sodium ions. One bound Na+ (Na1) contributes to the substrate binding, while the other Na+ (Na2) is thought to be involved in the conformational transiti...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/87985 |