Mixed longitudinal and cross-sectional analyses of deep gray matter and white matter using diffusion weighted images in premanifest and manifest Huntington’s disease

Changes in the brain of patients with Huntington's disease (HD) begin years before clinical onset, so it remains critical to identify biomarkers to track these early changes. Metrics derived from tensor modeling of diffusion-weighted MRIs (DTI), that indicate the microscopic brain structure, ca...

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Bibliographic Details
Main Authors: Beini Hu, Laurent Younes, Xuan Bu, Chin-Fu Liu, J. Tilak Ratnanather, Jane Paulsen, Nellie Georgiou-Karistianis, Michael I. Miller, Christopher Ross, Andreia V. Faria
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223001845