Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury

Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury

Background. Chemical spills are on the rise and inhalation of toxic chemicals may induce chemical acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Although the pathophysiology of ALI/ARDS is well understood, the absence of specific antidotes has limited the effectiveness of therap...

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Bibliographic Details
Main Authors: Frans J. Walther, José M. Hernández-Juviel, Larry M. Gordon, Alan J. Waring
Format: Article
Language:English
Published: PeerJ Inc. 2014-05-01
Series:PeerJ
Subjects:
Synthetic surfactant
Hydrochloric acid
Oxygenation
Ventilated rabbits
Surfactant protein B
Lung lavage
Online Access:https://peerj.com/articles/393.pdf

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https://peerj.com/articles/393.pdf

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