Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in <i>C. albicans</i> and <i>C. glabrata</i>

Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in <i>C. albicans</i> and <i>C. glabrata</i>

Histatin 5 (Hst 5) is an antimicrobial peptide produced in human saliva with antifungal activity for opportunistic pathogen <i>Candida albicans</i>. Hst 5 binds to multiple cations including dimerization-inducing zinc (Zn<sup>2+</sup>), although the function of this capabilit...

Full description

Bibliographic Details
Main Authors: Hannah L. Norris, Rohitashw Kumar, Chih Yean Ong, Ding Xu, Mira Edgerton
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Fungi
Subjects:
<i>Candida albicans</i>
<i>Candida glabrata</i>
Histatin 5
P113
zinc
membrane disruption
Online Access:https://www.mdpi.com/2309-608X/6/3/124

Internet

https://www.mdpi.com/2309-608X/6/3/124

Similar Items