Genome Sequencing of Consanguineous Family Implicates Ubiquitin-Specific Protease 53 (<i>USP53</i>) Variant in Psychosis/Schizophrenia: Wild-Type Expression in Murine Hippocampal CA 1–3 and Granular Dentate with AMPA Synapse Interactions

Genome Sequencing of Consanguineous Family Implicates Ubiquitin-Specific Protease 53 (<i>USP53</i>) Variant in Psychosis/Schizophrenia: Wild-Type Expression in Murine Hippocampal CA 1–3 and Granular Dentate with AMPA Synapse Interactions

Psychosis is a severe mental disorder characterized by abnormal thoughts and perceptions (e.g., hallucinations) occurring quintessentially in schizophrenia and in several other neuropsychiatric disorders. Schizophrenia is widely considered as a neurodevelopmental disorder that onsets during teenage/...

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Bibliographic Details
Main Authors: Ambreen Kanwal, Sohail A. Sheikh, Faiza Aslam, Samina Yaseen, Zachary Beetham, Nathan Pankratz, Connie R. Clabots, Sadaf Naz, José V. Pardo
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
deubiquitinating enzyme (DUB)
intercellular junction
GRIA2
GRIP2
homozygosity mapping
Online Access:https://www.mdpi.com/2073-4425/14/10/1921

Internet

https://www.mdpi.com/2073-4425/14/10/1921

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