High-Resolution Transcriptomic Analysis of the Adaptive Response of <named-content content-type="genus-species">Staphylococcus aureus</named-content> during Acute and Chronic Phases of Osteomyelitis

ABSTRACT Osteomyelitis is a difficult-to-eradicate bone infection typically caused by Staphylococcus aureus. In this study, we investigated the in vivo transcriptional adaptation of S. aureus during bone infection. To this end, we determined the transcriptome of S. aureus during the acute (day 7) an...

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Main Authors: Anna K. Szafranska, Andrew P. A. Oxley, Diego Chaves-Moreno, Sarah A. Horst, Steffen Roßlenbroich, Georg Peters, Oliver Goldmann, Manfred Rohde, Bhanu Sinha, Dietmar H. Pieper, Bettina Löffler, Ruy Jauregui, Melissa L. Wos-Oxley, Eva Medina
Format: Article
Language:English
Published: American Society for Microbiology 2014-12-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01775-14