Development and Evaluation of Polymeric Nanosponge Hydrogel for Terbinafine Hydrochloride: Statistical Optimization, In Vitro and In Vivo Studies

Development and Evaluation of Polymeric Nanosponge Hydrogel for Terbinafine Hydrochloride: Statistical Optimization, In Vitro and In Vivo Studies

Terbinafine hydrochloride, although one of the prominent antifungal agents, suffers from low drug permeation owing to its hydrophobic nature. The approach of nanosponge formulation may thus help to resolve this concern. Thus, the present research was envisioned to fabricate the nanosponge hydrogel o...

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Bibliographic Details
Main Authors: Aditee Ghose, Bushra Nabi, Saleha Rehman, Shadab Md, Nabil A. Alhakamy, Osama A. A. Ahmad, Sanjula Baboota, Javed Ali
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Polymers
Subjects:
nanosponge
hydrogel
Box–Behnken design
pharmacokinetic
terbinafine hydrogel
Online Access:https://www.mdpi.com/2073-4360/12/12/2903

Internet

https://www.mdpi.com/2073-4360/12/12/2903

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