Incidence of the CHEK2 Germline Mutation and Its Impact on Clinicopathological Features, Treatment Responses, and Disease Course in Patients with Papillary Thyroid Carcinoma

The CHEK2 gene is involved in the repair of damaged DNA. CHEK2 germline mutations impair this repair mechanism, causing genomic instability and increasing the risk of various cancers, including papillary thyroid carcinoma (PTC). Here, we asked whether C...

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Bibliographic Details
Main Authors:	Danuta Gąsior-Perczak, Artur Kowalik, Krzysztof Gruszczyński, Agnieszka Walczyk, Monika Siołek, Iwona Pałyga, Sławomir Trepka, Estera Mikina, Tomasz Trybek, Janusz Kopczyński, Agnieszka Suligowska, Rafał Ślusarczyk, Agnieszka Gonet, Jarosław Jaskulski, Paweł Orłowski, Magdalena Chrapek, Stanisław Góźdź, Aldona Kowalska
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Cancers
Subjects:	papillary thyroid cancer <i>CHEK2</i> <i>CHEK2</i> missense mutation <i>CHEK2</i> truncating mutation risk stratification IVS2 + 1G &gt
Online Access:	https://www.mdpi.com/2072-6694/13/3/470

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https://www.mdpi.com/2072-6694/13/3/470

Incidence of the <i>CHEK2</i> Germline Mutation and Its Impact on Clinicopathological Features, Treatment Responses, and Disease Course in Patients with Papillary Thyroid Carcinoma

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