Preventive effects of inotodiol on polyinosinic–polycytidylic acid-induced inflammation in human dermal fibroblasts

Preventive effects of inotodiol on polyinosinic–polycytidylic acid-induced inflammation in human dermal fibroblasts

Double-strand RNA(dsRNA), which can induce inflammation, can be generated by necrotic keratinocytes in the skin environment. As an analog of dsRNA, polyinosinic–polycytidylic acid (poly(I:C)) is used to induce inflammation via the Toll-like Receptor 3 (TLR3) signaling pathway. Inotodiol, isolated fr...

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Bibliographic Details
Main Authors: Gun-Woo Won, Seung Hoon Lee, Mahesh Prakash Bhatta, Seung-Hyeon Choi, Cheong-Hae Oh, Jong-Tae Park, Jong-Il Park
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Inotodiol
Poly(I:C)
HDFs
Anti-inflammation
Toll-like receptor 3 signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023077642

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http://www.sciencedirect.com/science/article/pii/S2405844023077642

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