Phosphoglycerate mutase 5 exacerbates liver ischemia–reperfusion injury by activating mitochondrial fission
Abstract Although the death of hepatocytes is a crucial trigger of liver ischemia–reperfusion (I/R) injury, the regulation of liver I/R-induced hepatocyte death is still poorly understood. Phosphoglycerate mutase 5 (PGAM5), a mitochondrial Serine/Threonine protein phosphatase, regulates mitochondria...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-024-58748-7 |