2D electrophoresis image brightness correction based on gradient interval histogram

Abstract Background Two-dimensional electrophoresis (2DE) is one of the most widely applied techniques in comparative proteomics. The basic task of 2DE is to identify differential protein expression by quantitative analysis of 2DE images. To reduce the errors of spot quantification in 2DE images, a...

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Bibliographic Details
Main Authors: Qiaofeng Ou, Jiabing Xiao, Lei Yu, Kaizhi Wu, Bangshu Xiong
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3432-y