The Role of Astrocytes in Synapse Loss in Alzheimer's Disease: A Systematic Review

Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people worldwide. One pathological feature of progressing AD is the loss of synapses. This is the strongest correlate of cognitive decline. Astrocytes, as an essential part of the tripartite synapse, play a role...

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Bibliographic Details
Main Authors: Lianne A. Hulshof, Danny van Nuijs, Elly M. Hol, Jinte Middeldorp
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.899251/full