A new experimental model for acute hepatic failure in rats Novo modelo experimental em ratos para insuficiência hepática aguda

PURPOSE: To develop a reliable surgical model of acute hepatic failure and hyperammonemia in rats that avoids porto-systemic shunt and bile duct ligation, applicable to hepatic encephalopathy research. METHODS: The pedicles of right lateral and caudate lobes were exposed and clamped. One hour later,...

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Main Authors: Antonio Roberto Franchi Teixeira, Marcel Cerqueira Cesar Machado, Márcia Saldanha Kubrusly, Nilza Trindade Molan, Marta Bellodi-Privato, Kátia Regina Leite, Luiz Augusto Carneiro D'Albuquerque
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2010-06-01
Series:Acta Cirúrgica Brasileira
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000300009