Semaphorin 3 C enhances putative cancer stemness and accelerates peritoneal dissemination in pancreatic cancer

Semaphorin 3 C enhances putative cancer stemness and accelerates peritoneal dissemination in pancreatic cancer

Abstract Purpose Semaphorins, axon guidance cues in neuronal network formation, have been implicated in cancer progression. We previously identified semaphorin 3 C (SEMA3C) as a secreted protein overexpressed in pancreatic ductal adenocarcinoma (PDAC). We, therefore, hypothesized that SEMA3C support...

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Bibliographic Details
Main Authors: Satoshi Tomizawa, Shigetsugu Takano, Ryotaro Eto, Tsukasa Takayashiki, Satoshi Kuboki, Masayuki Ohtsuka
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cancer Cell International
Subjects:
SEMA3C
Pancreatic cancer
Peritoneal dissemination
Chemoresistance
Cancer stemness
Online Access:https://doi.org/10.1186/s12935-023-03008-3

Internet

https://doi.org/10.1186/s12935-023-03008-3

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