Mimicking the in vivo Environment – The Effect of Crowding on RNA and Biomacromolecular Folding and Activity

In vitro studies on macromolecules, like proteins and nucleic acids, are mostly carried out in highly diluted systems where the molecules are studied under artificial conditions. These experimental conditions are optimized for both the system under investigation and the technique used. However, the...

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Bibliographic Details
Main Authors: Erica Fiorini, Richard Börner, Roland K. O. Sigel
Format: Article
Language:deu
Published: Swiss Chemical Society 2015-04-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/5733