Revealing underlying regulatory mechanisms of LINC00313 in Osimertinib-resistant LUAD cells by ceRNA network analysis

Revealing underlying regulatory mechanisms of LINC00313 in Osimertinib-resistant LUAD cells by ceRNA network analysis

Background: Osimertinib, a third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), is the preferred treatment for EGFR-mutated lung cancer. However, acquired resistance inevitably develops. While non-coding RNAs have been implicated in lung cancer through various func...

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Bibliographic Details
Main Authors: Dandan Ding, Chenguang Xu, Jufeng Zhang, Ying Zhang, Lipeng Xue, Jingjing Song, Zhiming Luo, Xiaoyu Hong, Jian Wang, Weicheng Liang, Xingyang Xue
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Translational Oncology
Subjects:
Osimertinib resistance
EGFR-TKIs
LINC00313
lncRNA-miRNA-mRNA (ceRNA)
Lung adenocarcinoma (LUAD)
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000214

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http://www.sciencedirect.com/science/article/pii/S1936523324000214

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