An emerging master inducer and regulator for epithelial-mesenchymal transition and tumor metastasis: extracellular and intracellular ATP and its molecular functions and therapeutic potential

An emerging master inducer and regulator for epithelial-mesenchymal transition and tumor metastasis: extracellular and intracellular ATP and its molecular functions and therapeutic potential

Abstract Despite the rapid development of therapeutic strategies in cancer treatment, metastasis remains the major cause of cancer-related death and scientific challenge. Epithelial-Mesenchymal Transition (EMT) plays a crucial role in cancer invasion and progression, a process by which tumor cells l...

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Bibliographic Details
Main Authors: Yanyang Cao, Eileen Chen, Xuan Wang, Jingwen Song, Haiyun Zhang, Xiaozhuo Chen
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Cell International
Subjects:
Tumor microenvironment
Invasion
EMT
ATP internalization
Macropinocytosis
Purinergic receptor
Online Access:https://doi.org/10.1186/s12935-023-02859-0

Internet

https://doi.org/10.1186/s12935-023-02859-0

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