SARS-CoV-2 RBD and Its Variants Can Induce Platelet Activation and Clearance: Implications for Antibody Therapy and Vaccinations against COVID-19

The COVID-19 pandemic caused by SARS-CoV-2 virus is an ongoing global health burden. Severe cases of COVID-19 and the rare cases of COVID-19 vaccine-induced-thrombotic-thrombocytopenia (VITT) are both associated with thrombosis and thrombocytopenia; however, the underlying mechanisms remain inadequa...

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Main Authors: Xiaoying Ma, Jady Liang, Guangheng Zhu, Preeti Bhoria, Aron A. Shoara, Daniel T. MacKeigan, Christopher J. Khoury, Sladjana Slavkovic, Lisha Lin, Danielle Karakas, Ziyan Chen, Viktor Prifti, Zhenze Liu, Chuanbin Shen, Yuchong Li, Cheng Zhang, Jiayu Dou, Zack Rousseau, Jiamin Zhang, Tiffany Ni, Xi Lei, Pingguo Chen, Xiaoyu Wu, Hamed Shaykhalishahi, Samira Mubareka, Kim A. Connelly, Haibo Zhang, Ori Rotstein, Heyu Ni
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0124