Contribution of Ras farnesyl transferase, MAP kinase and cytochrome P-450 metabolites to endothelin-1 induced hypertension

Contribution of Ras farnesyl transferase, MAP kinase and cytochrome P-450 metabolites to endothelin-1 induced hypertension

Endothelin 1 (ET-1) is vasoactive peptide that acts via ET-A receptors coupling inducing vascular smooth muscle cell proliferation and contraction. ET-1 is involved in the development and maintenance of hypertension. Aim of this study was to determine the contribution of Ras farnesyl transferase,...

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Bibliographic Details
Main Authors: Farid Ljuca, Gorazd Drevenšek, Enver Zerem
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2011-05-01
Series:Biomolecules & Biomedicine
Subjects:
endothelin-1
hypertension
cytochrome P-450
Ras farnesyl transferase
mitogen activated protein kinase
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/2586

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/2586

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