Interaction between <i>KLOTHO</i>-VS Heterozygosity and <i>APOE</i> ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease

Interaction between <i>KLOTHO</i>-VS Heterozygosity and <i>APOE</i> ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease

<i>KLOTHO</i>-VS heterozygosity (<i>KL</i>-VS<sup>het+</sup>) promotes longevity and protects against cognitive decline in aging. To determine whether <i>KL</i>-VS<sup>het+</sup> mitigates Alzheimer’s disease (AD) progression, we used longi...

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Bibliographic Details
Main Authors: Xi Richard Chen, Yongzhao Shao, Martin J. Sadowski, on behalf of the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
Alzheimer’s disease
<i>KLOTHO</i>
<i>APOE</i>
cognitive decline
aging
Online Access:https://www.mdpi.com/2073-4425/14/4/917

Internet

https://www.mdpi.com/2073-4425/14/4/917

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