Sestrin2 provides cerebral protection through activation of Nrf2 signaling in microglia following subarachnoid hemorrhage

Sestrin2 provides cerebral protection through activation of Nrf2 signaling in microglia following subarachnoid hemorrhage

Subarachnoid hemorrhage (SAH) is a neurological emergency characterized by dysfunctional inflammatory response. However, no effective therapeutic options have been reported so far. Microglia polarization has been proposed to exert an essential role in modulating inflammatory response after SAH. Sest...

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Bibliographic Details
Main Authors: Youqing Yang, Han Ding, Chenxing Yang, Jie Wu, Youyuan Bao, Shihai Lan, Lin Zhou, Lu Zhou, Bangliang Liu, Tao Hong, Xichen Wan, Xiao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
subarachnoid hemorrhage
microglial polarization
sestrin2
neuroinflammation
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1089576/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1089576/full

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