Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients.

BACKGROUND: Previously, we have examined the methylation status of SLC19A3 (solute carrier family 19, member 3) promoter and found that SLC19A3 was epigenetically down-regulated in gastric cancer. Here, we aim to develop a new biomarker for cancer diagnosis using methylated SLC19A3 DNA in plasma. ME...

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Bibliographic Details
Main Authors: Enders K O Ng, Candy P H Leung, Vivian Y Shin, Chris L P Wong, Edmond S K Ma, Hong Chuan Jin, Kent-Man Chu, Ava Kwong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138782?pdf=render