Body mass index, genetic susceptibility, and Alzheimer's disease: a longitudinal study based on 475,813 participants from the UK Biobank

Body mass index, genetic susceptibility, and Alzheimer's disease: a longitudinal study based on 475,813 participants from the UK Biobank

Abstract Background The association between body mass index (BMI) and Alzheimer's disease (AD) remains controversial. Genetic and environmental factors are now considered contributors to AD risk. However, little is known about the potential interaction between genetic risk and BMI on AD risk. O...

Full description

Bibliographic Details
Main Authors: Shiqi Yuan, Wentao Wu, Wen Ma, Xiaxuan Huang, Tao Huang, MIn Peng, Anding Xu, Jun Lyu
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Translational Medicine
Subjects:
Body mass index (BMI)
Genetic susceptibility
Alzheimer's disease (AD)
Bidirectional Mendelian randomization (MR)
UK Biobank
Online Access:https://doi.org/10.1186/s12967-022-03621-2

Internet

https://doi.org/10.1186/s12967-022-03621-2

Similar Items