A pilot study of add-on oral hypoglycemic agents in treatment-naïve genotype-1 chronic hepatitis C patients receiving peginterferon alfa-2b plus ribavirin

A pilot study of add-on oral hypoglycemic agents in treatment-naïve genotype-1 chronic hepatitis C patients receiving peginterferon alfa-2b plus ribavirin

Insulin resistance (IR) affects sustained virological response (SVR) to peginterferon alfa plus ribavirin (PR) in patients with chronic hepatitis C (CHC). Whether add-on oral hypoglycemic agents (OHAs) to PR improve SVR remains unclear; therefore, we conducted a prospective, randomized pilot trial o...

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Bibliographic Details
Main Authors: Ching-Sheng Hsu, Shih-Jer Hsu, Hans Hsienhong Lin, Tai-Chung Tseng, Chia-Chi Wang, Ding-Shinn Chen, Jia-Horng Kao
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of the Formosan Medical Association
Subjects:
hepatitis C virus
insulin resistance
oral hypoglycemic agents
pegylated interferon
randomized controlled trial
sustained virological response
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664614001788

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http://www.sciencedirect.com/science/article/pii/S0929664614001788

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