Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage

During the reprogramming of mouse embryonic fibroblasts (MEFs) to induced pluripotent stem cells, the activation of pluripotency genes such as NANOG occurs after the mesenchymal to epithelial transition. Here we report that both adult stem cells (neural stem cells) and differentiated cells (astrocyt...

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Bibliographic Details
Main Authors: Steven A. Jackson, Zachariah P.G. Olufs, Khoa A. Tran, Nur Zafirah Zaidan, Rupa Sridharan
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116000266