Plasma C4d Correlates With C4d Deposition in Kidneys and With Treatment Response in Lupus Nephritis Patients

Plasma C4d Correlates With C4d Deposition in Kidneys and With Treatment Response in Lupus Nephritis Patients

ObjectiveTo examine whether C4d plasma levels correlate with treatment response and C4d kidney deposition in systemic lupus erythematosus (SLE) with lupus nephritis (LN).MethodsC4d plasma levels were analyzed by a unique assay specifically detecting C4d arising from complement activation and C4 plas...

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Bibliographic Details
Main Authors: Myriam Martin, Rebecca Trattner, Sara C. Nilsson, Albin Björk, Agneta Zickert, Anna M. Blom, Iva Gunnarsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
complement
C4d
lupus nephritis
treatment response
kidney deposition
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.582737/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.582737/full

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