Single molecule counting and assessment of random molecular tagging errors with transposable giga-scale error-correcting barcodes

Single molecule counting and assessment of random molecular tagging errors with transposable giga-scale error-correcting barcodes

Abstract Background RNA-Seq measures gene expression by counting sequence reads belonging to unique cDNA fragments. Molecular barcodes commonly in the form of random nucleotides were recently introduced to improve gene expression measures by detecting amplification duplicates, but are susceptible to...

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Bibliographic Details
Main Authors: Billy T. Lau, Hanlee P. Ji
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Subjects:
Transcriptome
RNA-Seq
Molecular barcoding
Online Access:http://link.springer.com/article/10.1186/s12864-017-4141-4

Internet

http://link.springer.com/article/10.1186/s12864-017-4141-4

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