Single molecule counting and assessment of random molecular tagging errors with transposable giga-scale error-correcting barcodes
Abstract Background RNA-Seq measures gene expression by counting sequence reads belonging to unique cDNA fragments. Molecular barcodes commonly in the form of random nucleotides were recently introduced to improve gene expression measures by detecting amplification duplicates, but are susceptible to...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-09-01
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| Series: | BMC Genomics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12864-017-4141-4 |