Tumor Antigenicity and a Pre-Existing Adaptive Immune Response in Advanced BRAF Mutant Colorectal Cancers

Tumor Antigenicity and a Pre-Existing Adaptive Immune Response in Advanced BRAF Mutant Colorectal Cancers

The main hypothesis of this study is that gene expression profiles (GEPs) integrating both tumor antigenicity and a pre-existing adaptive immune response can be used to generate distinct immune-related signatures of BRAF mutant colorectal cancers (BRAF-CRCs) to identify actionable biomarkers predict...

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Bibliographic Details
Main Authors: Elena Bolzacchini, Laura Libera, Sarah E. Church, Nora Sahnane, Raffaella Bombelli, Nunzio Digiacomo, Monica Giordano, Guido Petracco, Fausto Sessa, Carlo Capella, Daniela Furlan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
BRAF mutation
colorectal cancer
immune checkpoint inhibitors
PanCancer IO 360
NanoString
MSI
Online Access:https://www.mdpi.com/2072-6694/14/16/3951

Internet

https://www.mdpi.com/2072-6694/14/16/3951

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