Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

Introduction: Downregulation of brain-derived neurotrophic factor (BDNF) and its cognate neurotrophin receptor, TrkB, were observed during the progression of dementia, but whether the Alzheimer's disease (AD) pathological lesions diffuse plaques, (DPs), neuritic plaques (NPs), and neurofibrilla...

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Bibliographic Details
Main Authors: Stephen D. Ginsberg, Michael H. Malek-Ahmadi, Melissa J. Alldred, Yinghua Chen, Kewei Chen, Moses V. Chao, Scott E. Counts, Elliott J. Mufson
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Brain-derived neurotrophic factor
Microarray
Mild cognitive impairment
Neuritic plaques
Neurofibrillary tangles
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119302086

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http://www.sciencedirect.com/science/article/pii/S0969996119302086

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