Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gamma.

Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gamma.

Peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of glucose and lipid metabolism and therefore an important pharmacological target to combat metabolic diseases. Since the currently used full PPARγ agonists display serious side effects, identification of novel ligands, part...

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Bibliographic Details
Main Authors: Atanas G Atanasov, Martina Blunder, Nanang Fakhrudin, Xin Liu, Stefan M Noha, Clemens Malainer, Matthias P Kramer, Amina Cocic, Olaf Kunert, Andreas Schinkovitz, Elke H Heiss, Daniela Schuster, Verena M Dirsch, Rudolf Bauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632601?pdf=render

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http://europepmc.org/articles/PMC3632601?pdf=render

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