ASPN Synergizes with HAPLN1 to Inhibit the Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells and Extracellular Matrix Mineralization of Osteoblasts

ASPN Synergizes with HAPLN1 to Inhibit the Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells and Extracellular Matrix Mineralization of Osteoblasts

Objective Bone marrow mesenchymal stromal cells (BMSCs) are major sources of osteogenic precursor cells in bone remodeling, which directly participate in osteoporosis (OP) progression. However, the involved specific mechanisms of BMSCs in OP warrant mass investigations. Initially, our bioinformatics...

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Bibliographic Details
Main Authors: Guohui Zhou, Xinmin Yan, Zhenfei Chen, Xing Zeng, Fangqian Wu
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Orthopaedic Surgery
Subjects:
ASPN
Bone marrow mesenchymal stromal cells
HAPLN1
Osteogenic differentiation
Osteoporosis
Online Access:https://doi.org/10.1111/os.13803

Internet

https://doi.org/10.1111/os.13803

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