Improvement of cognitive impairment in female type 2 diabetes mellitus mice by spironolactone

Patients with type 2 diabetes mellitus (T2DM) exhibit more severe cognitive decline in females compared with males; however, the preventive approach to this gender-specific cognitive decline is still an enigma. Spironolactone is a potassium-sparing diuretic that also acts as an androgen receptor ant...

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Bibliographic Details
Main Authors: Akiko Sakata, Masaki Mogi, Jun Iwanami, Kana Tsukuda, Li-Juan Min, Fei Jing, Kousei Ohshima, Masaharu Ito, Masatsugu Horiuchi
Format: Article
Language:English
Published: SAGE Publications 2012-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311412810