Master mitotic kinases regulate viral genome delivery during papillomavirus cell entry

Human papillomavirus (HPV) coopts mitosis for nuclear entry by tethering the viral DNA to mitotic chromosomes, a process facilitated by the viral minor capsid protein L2. Here, Rizzato et al. show that L2 contains conserved phosphorylation motifs within the chromosome-binding region and provide evid...

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Bibliographic Details
Main Authors: Matteo Rizzato, Fuxiang Mao, Florian Chardon, Kun-Yi Lai, Ruth Villalonga-Planells, Hannes C. A. Drexler, Marion E. Pesenti, Mert Fiskin, Nora Roos, Kelly M. King, Shuaizhi Li, Eduardo R. Gamez, Lilo Greune, Petra Dersch, Claudia Simon, Murielle Masson, Koenraad Van Doorslaer, Samuel K. Campos, Mario Schelhaas
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35874-w