In Silico Modeling Demonstrates that User Variability During Tumor Measurement Can Affect In Vivo Therapeutic Efficacy Outcomes

User measurement bias during subcutaneous tumor measurement is a source of variation in preclinical in vivo studies. We investigated whether this user variability could impact efficacy study outcomes, in the form of the false negative result rate when comparing treated and control groups. Two tumor...

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Bibliographic Details
Main Authors: Jake T Murkin, Hope E Amos, Daniel W Brough, Karl D Turley
Format: Article
Language:English
Published: SAGE Publishing 2022-11-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/11769351221139257