Cytokine-Induced Modulation of SARS-CoV2 Receptor Expression in Primary Human Nasal Epithelial Cells

<b>Background</b>: Viral entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) via the spike protein enables endocytosis into host cells using the ACE2 receptor and TMPRSS2. The frequent upper respiratory tract symptoms of COVID-19 and the localization of the virus to the...

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Bibliographic Details
Main Authors: Mahnaz Ramezanpour, Harrison Bolt, Karen Hon, George Spyro Bouras, Alkis James Psaltis, Peter-John Wormald, Sarah Vreugde
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/7/848