Genetic susceptibility to patient-reported xerostomia among long-term oropharyngeal cancer survivors

Abstract Genetic susceptibility for xerostomia, a common sequela of radiotherapy and chemoradiotherapy for head and neck cancer, is unknown. Therefore, to identify genetic variants associated with moderate to severe xerostomia, we conducted a GWAS of 359 long-term oropharyngeal cancer (OPC) survivor...

Full description

Bibliographic Details
Main Authors: Puja Aggarwal, Katherine A. Hutcheson, Robert Yu, Jian Wang, Clifton D. Fuller, Adam S. Garden, Ryan P. Goepfert, Jillian Rigert, Frank E. Mott, Charles Lu, Stephen Y. Lai, G. Brandon Gunn, Mark S. Chambers, Guojun Li, Chih-Chieh Wu, Ehab Y. Hanna, Erich M. Sturgis, Sanjay Shete
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10538-9