The repeat region of the circumsporozoite protein is critical for sporozoite formation and maturation in Plasmodium.

The circumsporozoite protein (CSP) is the major surface protein of the sporozoite stage of malaria parasites and has multiple functions as the parasite develops and then migrates from the mosquito midgut to the mammalian liver. The overall structure of CSP is conserved among Plasmodium species, cons...

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Bibliographic Details
Main Authors: David J P Ferguson, Amanda E Balaban, Eva-Maria Patzewitz, Richard J Wall, Christine S Hopp, Benoit Poulin, Asif Mohmmed, Pawan Malhotra, Alida Coppi, Photini Sinnis, Rita Tewari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113923&type=printable