B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis. Herein, a borane-catalysed hydroboration of nitriles to give primary amines is reported. Good yields (48–95%) and chemosel...

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Bibliographic Details
Main Authors: Filip Meger, Alexander C. W. Kwok, Franziska Gilch, Dominic R. Willcox, Alex J. Hendy, Kieran Nicholson, Andrew D. Bage, Thomas Langer, Thomas A. Hunt, Stephen P. Thomas
Format: Article
Language:English
Published: Beilstein-Institut 2022-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
boron
catalysis
hydroboration
nitrile
transborylation
Online Access:https://doi.org/10.3762/bjoc.18.138

Internet

https://doi.org/10.3762/bjoc.18.138

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