Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM

Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM

Abstract Background Multigene panel tests for breast cancer predisposition routinely include ATM as it is now a well-established breast cancer predisposition gene. Methods We included ATM in a multigene panel test applied to the Australian Breast Cancer Family Registry (ABCFR), a population-based ca...

Full description

Bibliographic Details
Main Authors: Anne-Laure Renault, James G. Dowty, Jason A. Steen, Shuai Li, Ingrid M. Winship, Graham G. Giles, John L. Hopper, Melissa C. Southey, Tú Nguyen-Dumont
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Breast Cancer Research
Subjects:
ATM
Breast cancer predisposition
Genetic risk factors
Age-specific cumulative risk
Penetrance
Online Access:https://doi.org/10.1186/s13058-022-01518-y

Internet

https://doi.org/10.1186/s13058-022-01518-y

Similar Items