HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit

Host factor tRNAs facilitate the replication of retroviruses such as human immunodeficiency virus type 1 (HIV-1). HIV-1 uses human tRNA<sup>Lys3</sup> as the primer for reverse transcription, and the assembly of HIV-1 structural protein Gag at the plasma membrane (PM) is regulated by mat...

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Bibliographic Details
Main Authors: Danni Jin, Yiping Zhu, Heidi L. Schubert, Stephen P. Goff, Karin Musier-Forsyth
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/2/474