Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders

Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders

Abstract Background Prenatal alcohol exposure (PAE) affects embryonic development, causing a variable fetal alcohol spectrum disorder (FASD) phenotype with neuronal disorders and birth defects. We hypothesize that early alcohol-induced epigenetic changes disrupt the accurate developmental programmin...

Full description

Bibliographic Details
Main Authors: P. Auvinen, J. Vehviläinen, H. Marjonen, V. Modhukur, J. Sokka, E. Wallén, K. Rämö, L. Ahola, A. Salumets, T. Otonkoski, H. Skottman, M. Ollikainen, R. Trokovic, H. Kahila, N. Kaminen-Ahola
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Medicine
Subjects:
Prenatal alcohol exposure
PAE
FASD
DNA methylation
Gene expression
Placenta
Online Access:https://doi.org/10.1186/s12916-022-02699-1

Internet

https://doi.org/10.1186/s12916-022-02699-1

Similar Items