Human MAP Tau Based Targeted Cytolytic Fusion Proteins

Some of the most promising small molecule toxins used to generate antibody drug conjugates (ADCs) include anti-mitotic agents (e.g., auristatin and its derivatives) which are designed to attack cancerous cells at their most vulnerable state during mitosis. We were interested in identifying a human c...

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Bibliographic Details
Main Authors: Olusiji A. Akinrinmade, Sandra Jordaan, Dmitrij Hristodorov, Radoslav Mladenov, Neelakshi Mungra, Shivan Chetty, Stefan Barth
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/5/3/36