Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity

Abstract Fungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has in...

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Bibliographic Details
Main Authors: Kamila Rząd, Iwona Gabriel, Ewa Paluszkiewicz, Aleksandra Kuplińska, Mateusz Olszewski, Agnieszka Chylewska, Aleksandra M. Dąbrowska, Katarzyna Kozłowska-Tylingo
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-54252-0